Raw powder peptides and lyophilized peptides are not the same, although they can appear similar in their dry form. Here’s a detailed distinction between the two:

Raw Powder Peptides

Production Method:

• Raw powder peptides are synthesized and then purified, resulting in a powder form without undergoing the freeze-drying process.
• These peptides are typically obtained directly after synthesis and purification steps.

Characteristics:

• They may still contain residual solvents or moisture from the synthesis process.
• Stability can vary, and they might not have the same level of purity and longevity as lyophilized peptides.

Storage and Handling:

• They generally require specific storage conditions to prevent degradation, often involving desiccation or refrigeration.
• Handling raw powder peptides involves careful consideration of potential residual moisture or solvents.

Lyophilized Peptides

Production Method:

• Lyophilized peptides undergo a freeze-drying process that removes all water content after synthesis and purification.
• This process involves freezing the peptide solution and then sublimating the ice under vacuum to obtain a dry powder.

Characteristics:

• They are in a completely dry, stable form with very low moisture content.
• The freeze-drying process increases their stability and shelf life significantly, making them more resistant to degradation.

Storage and Handling:

• Lyophilized peptides can typically be stored at room temperature, although refrigeration is recommended for long-term storage.
• They require reconstitution with a suitable solvent before use.

Summary

• Raw powder peptides are directly obtained after synthesis and purification and may contain residual moisture or solvents.
• Lyophilized peptides undergo an additional freeze-drying process, resulting in a more stable and long-lasting dry powder form.